Baldauf HM, Stegmann L, Schwarz SM, Ambiel I, Trotard M, Martin M, Burggraf M, Lenzi GM, Lejk H, Pan X, Fregoso OI, Lim ES, Abraham L, Nguyen LA, Rutsch F, König R, Kim B, Emerman M, Fackler OT, Keppler OT. Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2729-2734. doi:10.1073/pnas.1613635114. PubMed PMID: 28228523.
Fregoso OI, Emerman M. 2016. Activation of the DNA damage response is a conserved function of HIV-1 and HIV-2 Vpr that is independent of SLX4 recruitment. mBio 7(5):e01433-16. doi:10.1128/mBio.01433-16.
Akerman M, Fregoso OI, Das S, Ruse C, Jensen MA, Pappin DJ, Zhang MQ, Krainer AR. Differential connectivity of splicing activators and repressors to the human spliceosome. Genome Biol. 2015 Jun 6;16:119. doi: 10.1186/s13059-015-0682-5. PubMed PMID: 26047612; PubMed Central PMCID: PMC4502471.
Fregoso OI, Ahn J, Wang C, Mehrens J, Skowronski J, Emerman M. Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1. PLoS Pathog. 2013;9(7):e1003496. doi: 10.1371/journal.ppat.1003496. Epub 2013 Jul 18. PubMed PMID: 23874202; PubMed Central PMCID: PMC3715410.
Das S, Fregoso OI, Krainer AR. A new path to oncogene-induced senescence: at the crossroads of splicing and translation. Cell Cycle. 2013 May 15;12(10):1477-9. doi: 10.4161/cc.24749. Epub 2013 Apr 22. PubMed PMID: 23624837; PubMed Central PMCID: PMC3680522.
Fregoso OI, Das S, Akerman M, Krainer AR. Splicing-factor oncoprotein SRSF1 stabilizes p53 via RPL5 and induces cellular senescence. Mol Cell. 2013 Apr11;50(1):56-66. doi: 10.1016/j.molcel.2013.02.001. Epub 2013 Mar 7. PubMed PMID:23478443; PubMed Central PMCID: PMC3628402.
Bueno MT, Reyes D, Valdes L, Saheba A, Urias E, Mendoza C, Fregoso OI, Llano M. Poly(ADP-ribose) polymerase 1 promotes transcriptional repression of integrated retroviruses. J Virol. 2013 Mar;87(5):2496-507. doi:
10.1128/JVI.01668-12. Epub 2012 Dec 19. PubMed PMID: 23255787; PubMed Central PMCID: PMC3571415.
Lim ES, Fregoso OI, McCoy CO, Matsen FA, Malik HS, Emerman M. The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx. Cell Host Microbe. 2012 Feb
16;11(2):194-204. doi: 10.1016/j.chom.2012.01.004. Epub 2012 Jan 26. PubMed PMID: 22284954; PubMed Central PMCID: PMC3288607.
Sun S, Zhang Z, Fregoso O, Krainer AR. Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2. RNA. 2012 Feb;18(2):274-83. doi: 10.1261/rna.030486.111. Epub 2011 Dec 19. PubMed PMID: 22184459; PubMed Central PMCID: PMC3264914.
Bish RA, Fregoso OI, Piccini A, Myers MP. Conjugation of complex polyubiquitin chains to WRNIP1. J Proteome Res. 2008 Aug;7(8):3481-9. doi: 10.1021/pr800217q. Epub 2008 Jul 10. PubMed PMID: 18613717.
Llano M, Vanegas M, Fregoso O, Saenz D, Chung S, Peretz M, Poeschla EM. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes. J Virol. 2004 Sep;78(17):9524-37. PubMed PMID: 15308744; PubMed Central PMCID: PMC506940.
DIRECT LINK TO ALL PUBLICATIONS
Fregoso OI, Emerman M. 2016. Activation of the DNA damage response is a conserved function of HIV-1 and HIV-2 Vpr that is independent of SLX4 recruitment. mBio 7(5):e01433-16. doi:10.1128/mBio.01433-16.
Akerman M, Fregoso OI, Das S, Ruse C, Jensen MA, Pappin DJ, Zhang MQ, Krainer AR. Differential connectivity of splicing activators and repressors to the human spliceosome. Genome Biol. 2015 Jun 6;16:119. doi: 10.1186/s13059-015-0682-5. PubMed PMID: 26047612; PubMed Central PMCID: PMC4502471.
Fregoso OI, Ahn J, Wang C, Mehrens J, Skowronski J, Emerman M. Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1. PLoS Pathog. 2013;9(7):e1003496. doi: 10.1371/journal.ppat.1003496. Epub 2013 Jul 18. PubMed PMID: 23874202; PubMed Central PMCID: PMC3715410.
Das S, Fregoso OI, Krainer AR. A new path to oncogene-induced senescence: at the crossroads of splicing and translation. Cell Cycle. 2013 May 15;12(10):1477-9. doi: 10.4161/cc.24749. Epub 2013 Apr 22. PubMed PMID: 23624837; PubMed Central PMCID: PMC3680522.
Fregoso OI, Das S, Akerman M, Krainer AR. Splicing-factor oncoprotein SRSF1 stabilizes p53 via RPL5 and induces cellular senescence. Mol Cell. 2013 Apr11;50(1):56-66. doi: 10.1016/j.molcel.2013.02.001. Epub 2013 Mar 7. PubMed PMID:23478443; PubMed Central PMCID: PMC3628402.
Bueno MT, Reyes D, Valdes L, Saheba A, Urias E, Mendoza C, Fregoso OI, Llano M. Poly(ADP-ribose) polymerase 1 promotes transcriptional repression of integrated retroviruses. J Virol. 2013 Mar;87(5):2496-507. doi:
10.1128/JVI.01668-12. Epub 2012 Dec 19. PubMed PMID: 23255787; PubMed Central PMCID: PMC3571415.
Lim ES, Fregoso OI, McCoy CO, Matsen FA, Malik HS, Emerman M. The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx. Cell Host Microbe. 2012 Feb
16;11(2):194-204. doi: 10.1016/j.chom.2012.01.004. Epub 2012 Jan 26. PubMed PMID: 22284954; PubMed Central PMCID: PMC3288607.
Sun S, Zhang Z, Fregoso O, Krainer AR. Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2. RNA. 2012 Feb;18(2):274-83. doi: 10.1261/rna.030486.111. Epub 2011 Dec 19. PubMed PMID: 22184459; PubMed Central PMCID: PMC3264914.
Bish RA, Fregoso OI, Piccini A, Myers MP. Conjugation of complex polyubiquitin chains to WRNIP1. J Proteome Res. 2008 Aug;7(8):3481-9. doi: 10.1021/pr800217q. Epub 2008 Jul 10. PubMed PMID: 18613717.
Llano M, Vanegas M, Fregoso O, Saenz D, Chung S, Peretz M, Poeschla EM. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes. J Virol. 2004 Sep;78(17):9524-37. PubMed PMID: 15308744; PubMed Central PMCID: PMC506940.
DIRECT LINK TO ALL PUBLICATIONS
